RespirVec technology provides a simple, yet powerful and versatile way to provide protection against pathogens. RespirVec is a specially designed replication-deficient adenovirus that can activate the immune system in ways that conventional injectable vaccines cannot. RespirVec has the potential to stimulate an immune response that more closely mimics an actual pathogen infection and may provide both antibody and cell-mediated immunity, similar to what occurs following a natural infection.
RespirVec is designed to be administered intranasally instead of using a needle. This approach has several important advantages including easy, painless administration and the potential mobilization of the mucosal immune system to provide a first line of immune defense at the site of pathogen entry.
We expect that RespirVec-based products will be manufactured easily and quickly with a short production cycle time using the well-characterized PER.C6® cell line for production.